If you wish to use another media player, look at their documentation on how to install GLSL shaders and modify the shader accordingly if needed.
1- Install mpv
2- Download the .glsl shader files here
3- Copy the .glsl files to %AppData%\mpv\shaders for Windows or ~/.config/mpv/shaders for Linux.
4- If mpv.conf does not exist in %AppData%\mpv\ or ~/.config/mpv, create an empty file and follow these instructions to optimize your configuration.
5- Add this line to mpv.conf to enable the shaders: glsl-shaders="~~/shaders/Anime4K_Hybrid_v2.0RC.glsl"
The file name might vary depending on the version, rename it accordingly.
Unlike HLSL, the GLSL shader can auto-detect the scaling factor and adjust its strength accordingly.