From ac02711992579042f606bf4636d68836d4eeccf0 Mon Sep 17 00:00:00 2001
From: kchu25 <skchu@wustl.edu>
Date: Wed, 21 Aug 2024 17:44:33 -0400
Subject: [PATCH] update

---
 README.md | 5 +++--
 1 file changed, 3 insertions(+), 2 deletions(-)

diff --git a/README.md b/README.md
index 79e6039..2d92c99 100644
--- a/README.md
+++ b/README.md
@@ -26,13 +26,14 @@ will give
 
 # Note
 
+### Default genomic background
 The information content $IC(\cdot)$ (i.e. the "letter height") of the $i$-th column $c_i$ in a position weight matrix (PWM) is 
 
 $$
-IC(c_i) = \sum_{\alpha}\,f_{\alpha i}\,\log_2 \frac{f_{\alpha i}}{\beta_\alpha}
+IC(c_i) = \sum_{\alpha}f_{\alpha i}\log_2 \frac{f_{\alpha i}}{\beta_\alpha}
 $$
 
-where $f_{\alpha i}$ the frequency of nucleotide $\alpha\in {A,C,G,T}$ at the $i$-th column of a PWM. The $4$-dimensional vector $\beta$ is the assumed genomic background
+where $f_{\alpha i}$ the frequency of nucleotide $\alpha\in\Set{A,C,G,T}$ at the $i$-th column of a PWM. The $4$-dimensional vector $\beta$ is the assumed genomic background
 
 By default, the background $\beta$ is assumed to be flat, i.e. $\beta=(0.25, 0.25,0.25,0.25)$.