This repository contains the implementation of the computational models presented in the paper "The Role of Astrocytes in Place Cell Formation: A computational modeling study" by Ioannis Polykretis and Konstantinos P. Michmizos.
MATLAB 2017 or higher.
Execute the file SingleTransientPlaceCell.m to run the model with the single-CA1-cell network. The file generates a plot demonstrating the gradual emergence and fading of the place field of the CA1 cell.
Execute the file PopulationTransientPlaceCells.m to run the model with the CA1-cell-population network. The file generates a plot demonstrating the encoding of a circular track in the place fields of the CA1 cell population.
The remaining files are callable functions that are used to run the two simulation files.
This research was supported by the National Center for Medical Rehabilitation Research (NIH/NICHD) K12HD093427 Grant and the Rutgers Office of Research and Innovation. Ioannis Polykretis was partially funded by the Onassis Foundation Scholarship.