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I am looking at a very closely related population and I realized that p-value for a really important region is very reduced in univariate linear mixed model analysis with relatedness matrix. I looked at the region and I realized that the haplotype is at least 4Mb long in this specific population. would that be a reason for the fact that I am not seeing an elevated peak at that region with GWAS?
In general, how long should the haplotype be so that GEMMA doesn't mark the region as population structure.
Thanks.
The text was updated successfully, but these errors were encountered:
Hi,
I am looking at a very closely related population and I realized that p-value for a really important region is very reduced in univariate linear mixed model analysis with relatedness matrix. I looked at the region and I realized that the haplotype is at least 4Mb long in this specific population. would that be a reason for the fact that I am not seeing an elevated peak at that region with GWAS?
In general, how long should the haplotype be so that GEMMA doesn't mark the region as population structure.
Thanks.
The text was updated successfully, but these errors were encountered: