diff --git a/packages/nextjs/src/config/types.ts b/packages/nextjs/src/config/types.ts
index 965233d08b76..ffce8a8b0641 100644
--- a/packages/nextjs/src/config/types.ts
+++ b/packages/nextjs/src/config/types.ts
@@ -45,10 +45,12 @@ export type NextConfigObject = {
   experimental?: {
     instrumentationHook?: boolean;
     clientTraceMetadata?: string[];
+    serverComponentsExternalPackages?: string[]; // next < v15.0.0
   };
   productionBrowserSourceMaps?: boolean;
   // https://nextjs.org/docs/pages/api-reference/next-config-js/env
   env?: Record<string, string>;
+  serverExternalPackages?: string[]; // next >= v15.0.0
 };
 
 export type SentryBuildOptions = {
diff --git a/packages/nextjs/src/config/withSentryConfig.ts b/packages/nextjs/src/config/withSentryConfig.ts
index 543f271c1999..b94ce6187f97 100644
--- a/packages/nextjs/src/config/withSentryConfig.ts
+++ b/packages/nextjs/src/config/withSentryConfig.ts
@@ -17,6 +17,35 @@ import { constructWebpackConfigFunction } from './webpack';
 let showedExportModeTunnelWarning = false;
 let showedExperimentalBuildModeWarning = false;
 
+// Packages we auto-instrument need to be external for instrumentation to work
+// Next.js externalizes some packages by default, see: https://nextjs.org/docs/app/api-reference/config/next-config-js/serverExternalPackages
+// Others we need to add ourselves
+export const DEFAULT_SERVER_EXTERNAL_PACKAGES = [
+  'ai',
+  'amqplib',
+  'connect',
+  'dataloader',
+  'express',
+  'generic-pool',
+  'graphql',
+  '@hapi/hapi',
+  'ioredis',
+  'kafkajs',
+  'koa',
+  'lru-memoizer',
+  'mongodb',
+  'mongoose',
+  'mysql',
+  'mysql2',
+  'knex',
+  'pg',
+  'pg-pool',
+  '@node-redis/client',
+  '@redis/client',
+  'redis',
+  'tedious',
+];
+
 /**
  * Modifies the passed in Next.js configuration with automatic build-time instrumentation and source map upload.
  *
@@ -190,8 +219,10 @@ function getFinalConfigObject(
     );
   }
 
+  let nextMajor: number | undefined;
   if (nextJsVersion) {
     const { major, minor, patch, prerelease } = parseSemver(nextJsVersion);
+    nextMajor = major;
     const isSupportedVersion =
       major !== undefined &&
       minor !== undefined &&
@@ -229,6 +260,22 @@ function getFinalConfigObject(
 
   return {
     ...incomingUserNextConfigObject,
+    ...(nextMajor && nextMajor >= 15
+      ? {
+          serverExternalPackages: [
+            ...(incomingUserNextConfigObject.serverExternalPackages || []),
+            ...DEFAULT_SERVER_EXTERNAL_PACKAGES,
+          ],
+        }
+      : {
+          experimental: {
+            ...incomingUserNextConfigObject.experimental,
+            serverComponentsExternalPackages: [
+              ...(incomingUserNextConfigObject.experimental?.serverComponentsExternalPackages || []),
+              ...DEFAULT_SERVER_EXTERNAL_PACKAGES,
+            ],
+          },
+        }),
     webpack: constructWebpackConfigFunction(incomingUserNextConfigObject, userSentryOptions, releaseName),
   };
 }
diff --git a/packages/nextjs/test/config/withSentryConfig.test.ts b/packages/nextjs/test/config/withSentryConfig.test.ts
index f9db1a68771e..ee4b2d364c6a 100644
--- a/packages/nextjs/test/config/withSentryConfig.test.ts
+++ b/packages/nextjs/test/config/withSentryConfig.test.ts
@@ -1,4 +1,6 @@
-import { describe, expect, it, vi } from 'vitest';
+import { afterEach, describe, expect, it, vi } from 'vitest';
+import * as util from '../../src/config/util';
+import { DEFAULT_SERVER_EXTERNAL_PACKAGES } from '../../src/config/withSentryConfig';
 import { defaultRuntimePhase, defaultsObject, exportedNextConfig, userNextConfig } from './fixtures';
 import { materializeFinalNextConfig } from './testUtils';
 
@@ -22,10 +24,16 @@ describe('withSentryConfig', () => {
   it("works when user's overall config is an object", () => {
     const finalConfig = materializeFinalNextConfig(exportedNextConfig);
 
-    expect(finalConfig).toEqual(
+    const { webpack, experimental, ...restOfFinalConfig } = finalConfig;
+    // eslint-disable-next-line @typescript-eslint/no-unused-vars
+    const { webpack: _userWebpack, experimental: _userExperimental, ...restOfUserConfig } = userNextConfig;
+
+    expect(restOfFinalConfig).toEqual(restOfUserConfig);
+    expect(webpack).toBeInstanceOf(Function);
+    expect(experimental).toEqual(
       expect.objectContaining({
-        ...userNextConfig,
-        webpack: expect.any(Function), // `webpack` is tested specifically elsewhere
+        instrumentationHook: true,
+        serverComponentsExternalPackages: expect.arrayContaining(DEFAULT_SERVER_EXTERNAL_PACKAGES),
       }),
     );
   });
@@ -35,10 +43,21 @@ describe('withSentryConfig', () => {
 
     const finalConfig = materializeFinalNextConfig(exportedNextConfigFunction);
 
-    expect(finalConfig).toEqual(
+    const { webpack, experimental, ...restOfFinalConfig } = finalConfig;
+    const {
+      // eslint-disable-next-line @typescript-eslint/no-unused-vars
+      webpack: _userWebpack,
+      // eslint-disable-next-line @typescript-eslint/no-unused-vars
+      experimental: _userExperimental,
+      ...restOfUserConfig
+    } = exportedNextConfigFunction();
+
+    expect(restOfFinalConfig).toEqual(restOfUserConfig);
+    expect(webpack).toBeInstanceOf(Function);
+    expect(experimental).toEqual(
       expect.objectContaining({
-        ...exportedNextConfigFunction(),
-        webpack: expect.any(Function), // `webpack` is tested specifically elsewhere
+        instrumentationHook: true,
+        serverComponentsExternalPackages: expect.arrayContaining(DEFAULT_SERVER_EXTERNAL_PACKAGES),
       }),
     );
   });
@@ -75,4 +94,54 @@ describe('withSentryConfig', () => {
       consoleWarnSpy.mockRestore();
     }
   });
+
+  describe('server packages configuration', () => {
+    afterEach(() => {
+      vi.restoreAllMocks();
+    });
+
+    it('uses serverExternalPackages for Next.js 15+', () => {
+      vi.spyOn(util, 'getNextjsVersion').mockReturnValue('15.0.0');
+      const finalConfig = materializeFinalNextConfig(exportedNextConfig);
+
+      expect(finalConfig.serverExternalPackages).toBeDefined();
+      expect(finalConfig.serverExternalPackages).toEqual(expect.arrayContaining(DEFAULT_SERVER_EXTERNAL_PACKAGES));
+      expect(finalConfig.experimental?.serverComponentsExternalPackages).toBeUndefined();
+    });
+
+    it('uses experimental.serverComponentsExternalPackages for Next.js < 15', () => {
+      vi.spyOn(util, 'getNextjsVersion').mockReturnValue('14.0.0');
+      const finalConfig = materializeFinalNextConfig(exportedNextConfig);
+
+      expect(finalConfig.serverExternalPackages).toBeUndefined();
+      expect(finalConfig.experimental?.serverComponentsExternalPackages).toBeDefined();
+      expect(finalConfig.experimental?.serverComponentsExternalPackages).toEqual(
+        expect.arrayContaining(DEFAULT_SERVER_EXTERNAL_PACKAGES),
+      );
+    });
+
+    it('preserves existing packages in both versions', () => {
+      const existingPackages = ['@some/existing-package'];
+
+      vi.spyOn(util, 'getNextjsVersion').mockReturnValue('15.0.0');
+      const config15 = materializeFinalNextConfig({
+        ...exportedNextConfig,
+        serverExternalPackages: existingPackages,
+      });
+      expect(config15.serverExternalPackages).toEqual(
+        expect.arrayContaining([...existingPackages, ...DEFAULT_SERVER_EXTERNAL_PACKAGES]),
+      );
+
+      vi.spyOn(util, 'getNextjsVersion').mockReturnValue('14.0.0');
+      const config14 = materializeFinalNextConfig({
+        ...exportedNextConfig,
+        experimental: {
+          serverComponentsExternalPackages: existingPackages,
+        },
+      });
+      expect(config14.experimental?.serverComponentsExternalPackages).toEqual(
+        expect.arrayContaining([...existingPackages, ...DEFAULT_SERVER_EXTERNAL_PACKAGES]),
+      );
+    });
+  });
 });