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Wellcome Sanger Institute
- Wellcome Genome Campus
- https://www.sanger.ac.uk/group/parts-group/
- @jhepkema
sequencemodels
Fully convolutional deep learning variant effect predictor architecture
Data-driven design of context-specific regulatory elements
Sequence-based Modeling of single-cell ATAC-seq using Convolutional Neural Networks.
Deep learning model built to quantitatively predict the activities of developmental and housekeeping enhancers from DNA sequence in Drosophila melanogaster S2 cells
Open source code for AlphaFold 2.
A neural network framework for predicting the Hi-C chromatin interactions from megabase scale DNA sequence
Sequential regulatory activity predictions with deep convolutional neural networks.
a framework for training sequence-level deep learning networks
code to run sei and obtain sei and sequence class predictions
accurate prediction of promoter activity and variant effects from massive parallel reporter assays
Official repository for the paper "Large-scale clinical interpretation of genetic variants using evolutionary data and deep learning". Joint collaboration between the Marks lab and the OATML group.
Protein design and variant prediction using autoregressive generative models