From 96862884049efc98ec0becbf0fa90f16dd361ac9 Mon Sep 17 00:00:00 2001 From: lwjohnst86 Date: Thu, 29 Aug 2024 12:10:37 +0000 Subject: [PATCH] Project proposal: bhi --- data-raw/projects/proposals/bhi.yaml | 23 +++++++++++++++++++++++ 1 file changed, 23 insertions(+) create mode 100644 data-raw/projects/proposals/bhi.yaml diff --git a/data-raw/projects/proposals/bhi.yaml b/data-raw/projects/proposals/bhi.yaml new file mode 100644 index 0000000..82d4931 --- /dev/null +++ b/data-raw/projects/proposals/bhi.yaml @@ -0,0 +1,23 @@ +submitted_on: '2024-08-29' +full_name: Nuno Nogueira +github_username: nunonog +job_position: Postdoc researcher +phd_supervisor: '' +affiliation: Aarhus University +project_title: 'Investigating the Impact of Family-Based BMI Divergence on Premature + Mortality: Development and Application of a Pedigree-Based Homeostatic Index' +project_description: The proposed project seeks to explore how deviations from an + individual’s genetically-determined BMI, as calculated through familial relationships, + influence the risk of premature mortality. By constructing a family-based BMI Homeostatic + Index (BHI), we aim to capture the genetically-determined BMI for each individual + using data from multiple generations within families. This index will serve as a + measure of how much an individual’s BMI deviates from what would be expected based + on their genetic background.The project involves calculating the BHI by analyzing + BMI data across family members, taking into account the degree of relatedness between + individuals. By using a pedigree-based approach, the BHI will quantify the divergence + of an individual's BMI from their family's average, adjusted for factors such as + age and sex. This approach allows us to assess whether these deviations are associated + with increased mortality risk, offering insights into the genetic basis of obesity + and its health consequences. +agree_to_conditions: 'Yes' +