diff --git a/MIGRATION.md b/MIGRATION.md
index e60f5779db7c..80b14ae3cbc5 100644
--- a/MIGRATION.md
+++ b/MIGRATION.md
@@ -1,6 +1,7 @@
 <h1>Migration</h1>
 
 - [From version 7.x to 8.0.0](#from-version-7x-to-800)
+  - [Default keyboard shortcuts changed](#default-keyboard-shortcuts-changed)
   - [Manager addons are now rendered with React 18](#manager-addons-are-now-rendered-with-react-18)
   - [Removal of `storiesOf`-API](#removal-of-storiesof-api)
   - [Removed deprecated shim packages](#removed-deprecated-shim-packages)
@@ -70,17 +71,17 @@
   - [Addon author changes](#addon-author-changes)
     - [Removed `config` preset](#removed-config-preset-1)
 - [From version 7.5.0 to 7.6.0](#from-version-750-to-760)
-    - [CommonJS with Vite is deprecated](#commonjs-with-vite-is-deprecated)
-    - [Using implicit actions during rendering is deprecated](#using-implicit-actions-during-rendering-is-deprecated)
-    - [typescript.skipBabel deprecated](#typescriptskipbabel-deprecated)
-    - [Primary doc block accepts of prop](#primary-doc-block-accepts-of-prop)
-    - [Addons no longer need a peer dependency on React](#addons-no-longer-need-a-peer-dependency-on-react)
+  - [CommonJS with Vite is deprecated](#commonjs-with-vite-is-deprecated)
+  - [Using implicit actions during rendering is deprecated](#using-implicit-actions-during-rendering-is-deprecated)
+  - [typescript.skipBabel deprecated](#typescriptskipbabel-deprecated)
+  - [Primary doc block accepts of prop](#primary-doc-block-accepts-of-prop)
+  - [Addons no longer need a peer dependency on React](#addons-no-longer-need-a-peer-dependency-on-react)
 - [From version 7.4.0 to 7.5.0](#from-version-740-to-750)
-    - [`storyStoreV6` and `storiesOf` is deprecated](#storystorev6-and-storiesof-is-deprecated)
-    - [`storyIndexers` is replaced with `experimental_indexers`](#storyindexers-is-replaced-with-experimental_indexers)
+  - [`storyStoreV6` and `storiesOf` is deprecated](#storystorev6-and-storiesof-is-deprecated)
+  - [`storyIndexers` is replaced with `experimental_indexers`](#storyindexers-is-replaced-with-experimental_indexers)
 - [From version 7.0.0 to 7.2.0](#from-version-700-to-720)
-    - [Addon API is more type-strict](#addon-api-is-more-type-strict)
-    - [Addon-controls hideNoControlsWarning parameter is deprecated](#addon-controls-hidenocontrolswarning-parameter-is-deprecated)
+  - [Addon API is more type-strict](#addon-api-is-more-type-strict)
+  - [Addon-controls hideNoControlsWarning parameter is deprecated](#addon-controls-hidenocontrolswarning-parameter-is-deprecated)
 - [From version 6.5.x to 7.0.0](#from-version-65x-to-700)
   - [7.0 breaking changes](#70-breaking-changes)
     - [Dropped support for Node 15 and below](#dropped-support-for-node-15-and-below)
@@ -384,6 +385,10 @@
 
 ## From version 7.x to 8.0.0
 
+### Default keyboard shortcuts changed
+
+The default keyboard shortcuts have changed to avoid any conflicts with the browser's default shortcuts or when you are directly typing in the Manager. If you want to get the new default shortcuts, you can reset your shortcuts in the keyboard shortcuts panel by pressing the `Restore default` button.
+
 ### Manager addons are now rendered with React 18
 
 The UI added to the manager via addons is now rendered with React 18.
diff --git a/code/addons/outline/src/OutlineSelector.tsx b/code/addons/outline/src/OutlineSelector.tsx
index 012477bae60c..10d5eec131f6 100644
--- a/code/addons/outline/src/OutlineSelector.tsx
+++ b/code/addons/outline/src/OutlineSelector.tsx
@@ -20,8 +20,8 @@ export const OutlineSelector = memo(function OutlineSelector() {
 
   useEffect(() => {
     api.setAddonShortcut(ADDON_ID, {
-      label: 'Toggle Outline [O]',
-      defaultShortcut: ['O'],
+      label: 'Toggle Outline',
+      defaultShortcut: ['alt', 'O'],
       actionName: 'outline',
       showInMenu: false,
       action: toggleOutline,
diff --git a/code/addons/viewport/src/shortcuts.ts b/code/addons/viewport/src/shortcuts.ts
index 47fd37cbb996..974abe477d6d 100644
--- a/code/addons/viewport/src/shortcuts.ts
+++ b/code/addons/viewport/src/shortcuts.ts
@@ -1,4 +1,4 @@
-import type { API } from '@storybook/manager-api';
+import { type API } from '@storybook/manager-api';
 import { ADDON_ID } from './constants';
 import { globals as defaultGlobals } from './preview';
 
@@ -27,7 +27,7 @@ export const registerShortcuts = async (
 ) => {
   await api.setAddonShortcut(ADDON_ID, {
     label: 'Previous viewport',
-    defaultShortcut: ['shift', 'V'],
+    defaultShortcut: ['alt', 'shift', 'V'],
     actionName: 'previous',
     action: () => {
       updateGlobals({
@@ -38,7 +38,7 @@ export const registerShortcuts = async (
 
   await api.setAddonShortcut(ADDON_ID, {
     label: 'Next viewport',
-    defaultShortcut: ['V'],
+    defaultShortcut: ['alt', 'V'],
     actionName: 'next',
     action: () => {
       updateGlobals({
@@ -49,7 +49,7 @@ export const registerShortcuts = async (
 
   await api.setAddonShortcut(ADDON_ID, {
     label: 'Reset viewport',
-    defaultShortcut: ['alt', 'V'],
+    defaultShortcut: ['alt', 'control', 'V'],
     actionName: 'reset',
     action: () => {
       updateGlobals(defaultGlobals);
diff --git a/code/e2e-tests/manager.spec.ts b/code/e2e-tests/manager.spec.ts
index 367082e9391e..5ef2a975b4ea 100644
--- a/code/e2e-tests/manager.spec.ts
+++ b/code/e2e-tests/manager.spec.ts
@@ -21,9 +21,9 @@ test.describe('Manager UI', () => {
       await expect(sbPage.page.locator('.sidebar-container')).toBeVisible();
 
       // toggle with keyboard shortcut
-      await sbPage.page.locator('html').press('s');
+      await sbPage.page.locator('html').press('Alt+s');
       await expect(sbPage.page.locator('.sidebar-container')).not.toBeVisible();
-      await sbPage.page.locator('html').press('s');
+      await sbPage.page.locator('html').press('Alt+s');
       await expect(sbPage.page.locator('.sidebar-container')).toBeVisible();
 
       // toggle with menu item
@@ -51,9 +51,9 @@ test.describe('Manager UI', () => {
       await expectToolbarVisibility(true);
 
       // toggle with keyboard shortcut
-      await sbPage.page.locator('html').press('t');
+      await sbPage.page.locator('html').press('Alt+t');
       await expectToolbarVisibility(false);
-      await sbPage.page.locator('html').press('t');
+      await sbPage.page.locator('html').press('Alt+t');
       await expectToolbarVisibility(true);
 
       // toggle with menu item
@@ -75,9 +75,9 @@ test.describe('Manager UI', () => {
         await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
 
         // toggle with keyboard shortcut
-        await sbPage.page.locator('html').press('a');
+        await sbPage.page.locator('html').press('Alt+a');
         await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
-        await sbPage.page.locator('html').press('a');
+        await sbPage.page.locator('html').press('Alt+a');
         await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
       });
 
@@ -90,9 +90,9 @@ test.describe('Manager UI', () => {
         await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
 
         // toggle with keyboard shortcut
-        await sbPage.page.locator('html').press('a');
+        await sbPage.page.locator('html').press('Alt+a');
         await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
-        await sbPage.page.locator('html').press('a');
+        await sbPage.page.locator('html').press('Alt+a');
         await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
 
         // toggle with menu item
@@ -114,16 +114,16 @@ test.describe('Manager UI', () => {
         await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
 
         // toggle position with keyboard shortcut
-        await sbPage.page.locator('html').press('d');
+        await sbPage.page.locator('html').press('Alt+d');
         await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
         // TODO: how to assert panel position?
 
         // hide with keyboard shortcut
-        await sbPage.page.locator('html').press('a');
+        await sbPage.page.locator('html').press('Alt+a');
         await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
 
         // toggling position should also show the panel again
-        await sbPage.page.locator('html').press('d');
+        await sbPage.page.locator('html').press('Alt+d');
         await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
       });
     });
@@ -138,11 +138,11 @@ test.describe('Manager UI', () => {
       await expect(sbPage.page.locator('.sidebar-container')).toBeVisible();
 
       // toggle with keyboard shortcut
-      await sbPage.page.locator('html').press('f');
+      await sbPage.page.locator('html').press('Alt+f');
       await expect(sbPage.page.locator('#storybook-panel-root')).not.toBeVisible();
       await expect(sbPage.page.locator('.sidebar-container')).not.toBeVisible();
 
-      await sbPage.page.locator('html').press('f');
+      await sbPage.page.locator('html').press('Alt+f');
       await expect(sbPage.page.locator('#storybook-panel-root')).toBeVisible();
       await expect(sbPage.page.locator('.sidebar-container')).toBeVisible();
 
diff --git a/code/e2e-tests/preview-web.spec.ts b/code/e2e-tests/preview-web.spec.ts
index 6d8bf5526415..b4a96c4b6001 100644
--- a/code/e2e-tests/preview-web.spec.ts
+++ b/code/e2e-tests/preview-web.spec.ts
@@ -32,7 +32,7 @@ test.describe('preview-web', () => {
 
     // click outside, to remove focus from the input of the story, then press S to toggle sidebar
     await sbPage.previewRoot().click();
-    await sbPage.previewRoot().press('s');
+    await sbPage.previewRoot().press('Alt+s');
     await expect(sbPage.page.locator('.sidebar-container')).not.toBeVisible();
   });
 
@@ -47,7 +47,7 @@ test.describe('preview-web', () => {
 
     await expect(sbPage.page.locator('.sidebar-container')).toBeVisible();
 
-    await sbPage.previewRoot().getByRole('button').getByText('Submit').first().press('s');
+    await sbPage.previewRoot().getByRole('button').getByText('Submit').first().press('Alt+s');
     await expect(sbPage.page.locator('.sidebar-container')).not.toBeVisible();
   });
 });
diff --git a/code/lib/manager-api/src/modules/shortcuts.ts b/code/lib/manager-api/src/modules/shortcuts.ts
index d050028f8b8b..892afa652ab7 100644
--- a/code/lib/manager-api/src/modules/shortcuts.ts
+++ b/code/lib/manager-api/src/modules/shortcuts.ts
@@ -125,12 +125,12 @@ type API_AddonShortcutLabels = Record<string, string>;
 type API_AddonShortcutDefaults = Record<string, API_KeyCollection>;
 
 export const defaultShortcuts: API_Shortcuts = Object.freeze({
-  fullScreen: ['F'],
-  togglePanel: ['A'],
-  panelPosition: ['D'],
-  toggleNav: ['S'],
-  toolbar: ['T'],
-  search: ['/'],
+  fullScreen: ['alt', 'F'],
+  togglePanel: ['alt', 'A'],
+  panelPosition: ['alt', 'D'],
+  toggleNav: ['alt', 'S'],
+  toolbar: ['alt', 'T'],
+  search: [controlOrMetaKey(), 'K'],
   focusNav: ['1'],
   focusIframe: ['2'],
   focusPanel: ['3'],
@@ -139,7 +139,7 @@ export const defaultShortcuts: API_Shortcuts = Object.freeze({
   prevStory: ['alt', 'ArrowLeft'],
   nextStory: ['alt', 'ArrowRight'],
   shortcutsPage: [controlOrMetaKey(), 'shift', ','],
-  aboutPage: [','],
+  aboutPage: [controlOrMetaKey(), ','],
   escape: ['escape'], // This one is not customizable
   collapseAll: [controlOrMetaKey(), 'shift', 'ArrowUp'],
   expandAll: [controlOrMetaKey(), 'shift', 'ArrowDown'],
diff --git a/code/lib/manager-api/src/tests/shortcuts.test.js b/code/lib/manager-api/src/tests/shortcuts.test.js
index d5604a47f020..9aba57c756f7 100644
--- a/code/lib/manager-api/src/tests/shortcuts.test.js
+++ b/code/lib/manager-api/src/tests/shortcuts.test.js
@@ -54,7 +54,7 @@ describe('shortcuts api', () => {
     const { api, state } = initShortcuts({ store });
     store.setState(state);
 
-    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['F']);
+    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['alt', 'F']);
   });
 
   it('gets defaults including addon ones', async () => {
@@ -67,7 +67,7 @@ describe('shortcuts api', () => {
     await api.setAddonShortcut(mockAddonSecondShortcut.addon, mockAddonSecondShortcut.shortcut);
     await api.setAddonShortcut(mockSecondAddonShortcut.addon, mockSecondAddonShortcut.shortcut);
 
-    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['F']);
+    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['alt', 'F']);
     expect(api.getDefaultShortcuts()).toHaveProperty(
       `${mockAddonShortcut.addon}-${mockAddonShortcut.shortcut.actionName}`,
       mockAddonShortcut.shortcut.defaultShortcut
@@ -148,7 +148,7 @@ describe('shortcuts api', () => {
     const { api, state } = initShortcuts({ store });
     store.setState(state);
 
-    expect(api.getShortcutKeys().fullScreen).toEqual(['F']);
+    expect(api.getShortcutKeys().fullScreen).toEqual(['alt', 'F']);
   });
 
   it('sets addon shortcut with default value', async () => {
@@ -161,7 +161,7 @@ describe('shortcuts api', () => {
     await api.setAddonShortcut(mockAddonSecondShortcut.addon, mockAddonSecondShortcut.shortcut);
     await api.setAddonShortcut(mockSecondAddonShortcut.addon, mockSecondAddonShortcut.shortcut);
 
-    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['F']);
+    expect(api.getDefaultShortcuts()).toHaveProperty('fullScreen', ['alt', 'F']);
     expect(api.getDefaultShortcuts()).toHaveProperty(
       `${mockAddonShortcut.addon}-${mockAddonShortcut.shortcut.actionName}`,
       mockAddonShortcut.shortcut.defaultShortcut
@@ -184,7 +184,7 @@ describe('shortcuts api', () => {
     store.setState(state);
 
     expect(api.getShortcutKeys().fullScreen).toEqual(['Z']);
-    expect(api.getShortcutKeys().togglePanel).toEqual(['A']);
+    expect(api.getShortcutKeys().togglePanel).toEqual(['alt', 'A']);
   });
 
   it('sets defaults, ignoring anything persisted that is out of date', () => {
@@ -234,8 +234,8 @@ describe('shortcuts api', () => {
     await api.setShortcut(`${addon}-${shortcut.actionName}`, ['I']);
 
     await api.restoreAllDefaultShortcuts();
-    expect(api.getShortcutKeys().fullScreen).toEqual(['F']);
-    expect(api.getShortcutKeys().togglePanel).toEqual(['A']);
+    expect(api.getShortcutKeys().fullScreen).toEqual(['alt', 'F']);
+    expect(api.getShortcutKeys().togglePanel).toEqual(['alt', 'A']);
     expect(api.getShortcutKeys()[`${addon}-${shortcut.actionName}`]).toEqual(
       shortcut.defaultShortcut
     );
@@ -269,7 +269,7 @@ describe('shortcuts api', () => {
       `${mockAddonShortcut.addon}-${mockAddonShortcut.shortcut.actionName}`
     );
 
-    expect(api.getShortcutKeys().fullScreen).toEqual(['F']);
+    expect(api.getShortcutKeys().fullScreen).toEqual(['alt', 'F']);
     expect(api.getShortcutKeys().togglePanel).toEqual(['B']);
     expect(
       api.getShortcutKeys()[`${mockAddonShortcut.addon}-${mockAddonShortcut.shortcut.actionName}`]
diff --git a/code/ui/manager/src/components/sidebar/Search.tsx b/code/ui/manager/src/components/sidebar/Search.tsx
index 32415c056110..525337b8b2aa 100644
--- a/code/ui/manager/src/components/sidebar/Search.tsx
+++ b/code/ui/manager/src/components/sidebar/Search.tsx
@@ -122,8 +122,15 @@ const FocusKey = styled.code(({ theme }) => ({
   color: theme.base === 'light' ? theme.color.dark : theme.textMutedColor,
   userSelect: 'none',
   pointerEvents: 'none',
+  display: 'flex',
+  alignItems: 'center',
+  gap: 4,
 }));
 
+const FocusKeyCmd = styled.span({
+  fontSize: '14px',
+});
+
 const ClearIcon = styled.div(({ theme }) => ({
   position: 'absolute',
   top: 0,
@@ -352,7 +359,17 @@ export const Search = React.memo<{
               </SearchIconWrapper>
               {/* @ts-expect-error (TODO) */}
               <Input {...inputProps} />
-              {enableShortcuts && !isOpen && <FocusKey>{searchShortcut}</FocusKey>}
+              {enableShortcuts && !isOpen && (
+                <FocusKey>
+                  {searchShortcut === '⌘ K' ? (
+                    <>
+                      <FocusKeyCmd>⌘</FocusKeyCmd>K
+                    </>
+                  ) : (
+                    searchShortcut
+                  )}
+                </FocusKey>
+              )}
               {isOpen && (
                 <ClearIcon onClick={() => clearSelection()}>
                   <CloseIcon />