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remove CHR2 and END2 for CPX at the end of CleanVcf
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epiercehoffman committed Aug 8, 2023
1 parent 08f3961 commit 6feed34
Showing 1 changed file with 5 additions and 13 deletions.
18 changes: 5 additions & 13 deletions src/sv-pipeline/scripts/format_svtk_vcf_for_gatk.py
Original file line number Diff line number Diff line change
Expand Up @@ -137,19 +137,11 @@ def is_null(val):
is_ddup = svtype == 'CPX' and 'dDUP' in record.info.get('CPX_TYPE', '')
if svtype == 'BND' or svtype == 'INS' or svtype == 'CTX' or is_ddup:
record.stop = record.start + 1
if is_ddup:
# e.g. SOURCE=DUP_chrX:49151588-49151850
source = record.info.get('SOURCE', None)
if source is not None:
tokens = source.split(':')
chr2 = tokens[0].split('_')[-1]
end2 = int(tokens[-1].split('-')[0])
record.info['CHR2'] = chr2
record.info['END2'] = end2
else:
# Sometimes SOURCE is not set (may be from CPX review workflow)
record.info['CHR2'] = record.chrom
record.info['END2'] = record.stop
if svtype == 'CPX':
if 'CHR2' in record.info:
record.info.pop('CHR2')
if 'END2' in record.info:
record.info.pop('END2')
# Delete empty INFO fields (GATK does not like "." for non-String types)
keys = record.info.keys()
for k in keys:
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