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Move documentation to website #737
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Start moving documentation to website
mwalker174 d2e412e
Update readme
mwalker174 760a018
Couple of updates to GatherSampleEvidence page
mwalker174 076d6fc
Fix broken links
mwalker174 a40c943
Consolidate ref panel build
mwalker174 264189a
Camel case images
mwalker174 c91343b
Reviewer comments
mwalker174 b49c7ee
Resolve additional comments
mwalker174 76a5bab
Add scramble parameters for GatherSampleEvidence doc
mwalker174 43a2cf6
Fix link to prelim sample qc on joint calling page
mwalker174 b673f64
One last typo
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--- | ||
title: Acknowledgements | ||
description: Acknowledgements | ||
sidebar_position: 10 | ||
--- | ||
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The following resources were produced using data from the [All of Us Research Program](https://allofus.nih.gov/) | ||
and have been approved by the Program for public dissemination: | ||
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* Genotype filtering model: "aou_recalibrate_gq_model_file" in "inputs/values/resources_hg38.json" | ||
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The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional | ||
Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 | ||
OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: | ||
HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 | ||
OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 | ||
OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All | ||
of Us Research Program would not be possible without the partnership of its participants. |
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{ | ||
"label": "Advanced Guides", | ||
"position": 8, | ||
"position": 9, | ||
"link": { | ||
"type": "generated-index" | ||
} | ||
|
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--- | ||
title: Building reference panels | ||
description: Building reference panels for the single-sample pipeline | ||
sidebar_position: 4 | ||
slug: build_ref_panel | ||
--- | ||
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A custom reference panel for the [single-sample mode](/docs/gs/calling_modes#single-sample-mode) can be generated most easily using the | ||
[GATKSVPipelineBatch](https://github.com/broadinstitute/gatk-sv/blob/main/wdl/GATKSVPipelineBatch.wdl) workflow. | ||
This must be run on a standalone Cromwell server, as the workflow is unstable on Terra. | ||
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:::note | ||
Reference panels can also be generated by running the pipeline through joint calling on Terra, but there is | ||
currently no solution for automatically updating inputs. | ||
::: | ||
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We recommend copying the outputs from a Cromwell run to a permanent location by adding the following option to | ||
the workflow configuration file: | ||
``` | ||
"final_workflow_outputs_dir" : "gs://my-outputs-bucket", | ||
"use_relative_output_paths": false, | ||
``` | ||
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Here is an example of how to generate workflow input jsons from `GATKSVPipelineBatch` workflow metadata: | ||
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1. Get metadata from Cromwshell. | ||
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```shell | ||
cromshell -t60 metadata 38c65ca4-2a07-4805-86b6-214696075fef > metadata.json | ||
``` | ||
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2. Run the script. | ||
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```shell | ||
python scripts/inputs/create_test_batch.py \ | ||
--execution-bucket gs://my-exec-bucket \ | ||
--final-workflow-outputs-dir gs://my-outputs-bucket \ | ||
metadata.json \ | ||
> inputs/values/my_ref_panel.json | ||
``` | ||
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3. Build test files for batched workflows (google cloud project id required). | ||
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```shell | ||
python scripts/inputs/build_inputs.py \ | ||
inputs/values \ | ||
inputs/templates/test \ | ||
inputs/build/my_ref_panel/test \ | ||
-a '{ "test_batch" : "ref_panel_1kg" }' | ||
``` | ||
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4. Build test files for the single-sample workflow | ||
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```shell | ||
python scripts/inputs/build_inputs.py \ | ||
inputs/values \ | ||
inputs/templates/test/GATKSVPipelineSingleSample \ | ||
inputs/build/NA19240/test_my_ref_panel \ | ||
-a '{ "single_sample" : "test_single_sample_NA19240", "ref_panel" : "my_ref_panel" }' | ||
``` | ||
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5. Build files for a Terra workspace. | ||
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```shell | ||
python scripts/inputs/build_inputs.py \ | ||
inputs/values \ | ||
inputs/templates/terra_workspaces/single_sample \ | ||
inputs/build/NA12878/terra_my_ref_panel \ | ||
-a '{ "single_sample" : "test_single_sample_NA12878", "ref_panel" : "my_ref_panel" }' | ||
``` | ||
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Note that the inputs to `GATKSVPipelineBatch` may be used as resources | ||
for the reference panel and therefore should also be in a permanent location. |
4 changes: 2 additions & 2 deletions
4
...docs/advanced/development/_category_.json → ...te/docs/advanced/cromwell/_category_.json
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4 changes: 2 additions & 2 deletions
4
...ite/docs/advanced/development/cromwell.md → website/docs/advanced/cromwell/overview.md
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8 changes: 3 additions & 5 deletions
8
website/docs/gs/quick_start.md → ...ite/docs/advanced/cromwell/quick_start.md
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--- | ||
title: Best Practices Guide | ||
description: Guide for using GATK-SV | ||
sidebar_position: 4 | ||
--- | ||
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A comprehensive guide for the single-sample calling mode is available in [GATK Best Practices for Structural Variation | ||
Discovery on Single Samples](https://gatk.broadinstitute.org/hc/en-us/articles/9022653744283-GATK-Best-Practices-for-Structural-Variation-Discovery-on-Single-Samples). | ||
This material covers basic concepts of structural variant calling, specifics of SV VCF formatting, and | ||
advanced troubleshooting that also apply to the joint calling mode as well. This guide is intended to supplement | ||
documentation found here. | ||
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Users should also review the [Getting Started](/docs/gs/overview) section before attempting to perform SV calling. | ||
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The following sections also contain recommendations pertaining to data and call set QC: | ||
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- Preliminary sample QC in the [EvidenceQc module](/docs/modules/eqc#preliminary-sample-qc). | ||
- Assessment of completed call sets can be found on the [MainVcfQc module page](/docs/modules/mvqc). |
2 changes: 1 addition & 1 deletion
2
website/docs/run/_category_.json → website/docs/execution/_category_.json
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{ | ||
"label": "Run", | ||
"label": "Execution", | ||
"position": 4, | ||
"link": { | ||
"type": "generated-index" | ||
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Using lower case on all the other pages so I'm going to leave this alone for now