Synaptic inputs from identified bipolar and amacrine cells to a sparsely branched ganglion cell in rabbit retina

Data and code to produce the figures in:

Bordt, A., Perez, D., Tseng, L., Liu, W., Neitz, J., Patterson, S., Famiglietti, E., Marshak, D. (2019). Synaptic inputs from identified bipolar and amacrine cells to a sparsely branched ganglion cell in rabbit retina. Visual Neuroscience, 36, E004

Contents:

• FullFigures.m - code for the paper figures that were created with SBFSEM-tools. Loads neurons from the existing annotation database.
• FullFiguresCached.m - same as above but uses the neurons stored as .json files.
• c13525_synapses.m - code to mark synapses on c13525 (the labels and specialized markers were edited outside Matlab)
• ReciprocalSynapseAnalysis.m - code used to pull raw data on synapse distances, which was further analyzed outside Matlab.
• RabbitPaperCache.m - code used to save the neuron data into the .json files.

Use:

The annotation database for the rabbit connectome is edited constantly. While major changes are unlikely, there's no guarantee that the data associated with a given Neuron ID will remain the same long-term. For this reason, the annotations associated with a given neuron are preserved in .json files under the \data folder. You can run the figure code from the cached data with FullFiguresCached.m.

Dependencies:

• MATLAB 2015b or higher
• SBFSEM-tools, an open-source Matlab toolbox for connectomics visualization and analysis, used to mine the rabbit connectome developed in the Marc/Jones lab.

More information:

• Information on Viking and the rabbit connectome
• Article contact: [email protected]
• Software contact: [email protected]