UNICIT-microbiome

UNICIT microbiome analysis scripts of 16S rRNA gene sequencing and metagenomic shotgun sequencing data related to the publication: Verheijden RJ, van Eijs MJM, Paganelli FL, Viveen MC, Rogers MRC, Top J, May AM, van de Wijgert JHHM, Suijkerbuijk KPM; UNICIT-consortium. Gut microbiome and immune checkpoint inhibitor toxicity. Eur J Cancer. 2025 Jan 4;216:115221. doi: 10.1016/j.ejca.2025.115221).

This repository contains:

• The main analysis script
• The script for explaining the rationale for imputing zeros of bacterial groups before CLR-transformation