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Merge branch 'master' of github.com:genome/civic-server
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acoffman committed Jan 9, 2017
2 parents fa1de03 + a5807da commit 1a63841
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3 changes: 2 additions & 1 deletion text/glossary.yml
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Expand Up @@ -11,8 +11,9 @@ Evidence Level D: Case study evidence from individual case reports in peer revie
Evidence Level E: Inferential association made from experimental data.
Preclinical: Study using in vivo or in vitro models.
Predictive: Evidence pertaining to a variant's effect on therapeutic response.
Diagnostic: Evidence pertaining to a variant's impact on patient diagnosis.
Diagnostic: Evidence pertaining to a variant's impact on patient diagnosis (cancer subtype).
Prognostic: Evidence pertaining to a variant's impact on disease progression, severity, or patient survival.
Predisposing: Evidence pertaining to a variant's role in conferring susceptibility to a disease.
CIViC: Clinical Interpretations of Variants in Cancer
1-star: Evidence likely does not belong in CIViC. Claim is not supported well by experimental evidence. Results are not reproducible, or have very small sample size. No follow-up is done to validate novel claims.
2-stars: Evidence is not well supported by experimental data, and little follow-up data is available. Publication is from a journal with low academic impact. Experiments may lack proper controls, have small sample size, or are not statistically convincing.
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